The effects of prolactin on human sperm capacitation and acrosome reaction
Autor: | Dale W. Stovall, Robert B. Shabanowitz |
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Rok vydání: | 1991 |
Předmět: |
Male
endocrine system medicine.medical_specialty Time Factors Acrosome reaction Semen Biology Andrology Capacitation Internal medicine medicine Humans Acrosome Cells Cultured Dose-Response Relationship Drug urogenital system Obstetrics and Gynecology Biological activity Follicular fluid Sperm Prolactin Follicular Fluid Endocrinology Reproductive Medicine Female Sperm Capacitation hormones hormone substitutes and hormone antagonists |
Zdroj: | Fertility and Sterility. 56:960-966 |
ISSN: | 0015-0282 |
DOI: | 10.1016/s0015-0282(16)54672-x |
Popis: | Objective To study the effects of human prolactin (PRL) on human sperm capacitation and acrosome reaction. Design Acrosome reactions were induced by the addition of follicular fluid (FF) and progesterone (P). Experiments were performed to determine time and dose-dependent effects of PRL on sperm capacitation, potentiation of the acrosome reaction, decapacitating effects, and potential for PRL to induce an acrosome reaction. Results An average of 31.5% of spermatozoa underwent acrosome reaction with addition of FF and P. No time- or dose-dependent PRL effects on sperm capacitation or acrosome reaction were found ( P > 0.05). Conclusion Prolactin does not play an important role in human sperm capacitation or acrosome reaction. |
Databáze: | OpenAIRE |
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