Outcomes following repeat exenteration for locally advanced pelvic malignancy
| Autor: | Joshua Blake, Kilian G. M. Brown, Peter J Lee, Cherry E. Koh, Michael J. Solomon, Kirk K. S. Austin, Daniel Steffens, Marie Shella De Robles |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Locally advanced Asymptomatic 03 medical and health sciences Postoperative Complications 0302 clinical medicine medicine Humans Pelvic Neoplasms Proportional Hazards Models Retrospective Studies Pelvic exenteration Proportional hazards model business.industry Gastroenterology Margins of Excision Repeated measures design Cancer medicine.disease Pelvic Exenteration Surgery Treatment Outcome 030220 oncology & carcinogenesis Pelvic malignancy 030211 gastroenterology & hepatology Neoplasm Recurrence Local medicine.symptom Complication business |
| Zdroj: | Colorectal Disease. 23:646-652 |
| ISSN: | 1463-1318 1462-8910 |
| DOI: | 10.1111/codi.15402 |
| Popis: | AIM This study aims to assess surgical outcomes and survival following first, second and third pelvic exenterations for pelvic malignancy. METHOD Consecutive patients undergoing pelvic exenteration for pelvic malignancy at a quaternary referral centre from January 1994 and December 2017 were included. Demographics and surgical outcomes were compared between patients who underwent first, second and third pelvic exenterations by generalized mixed modelling with repeated measures. Survival was assessed using Cox proportional hazards models and Kaplan-Meier plots. RESULTS Of the 642 exenterations reviewed, 29 (4.5%) were second and 6 (0.9%) were third exenterations. Patients selected for repeat exenteration were more likely to have asymptomatic local recurrences detected on routine surveillance (P |
| Databáze: | OpenAIRE |
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