Chiral Nanochannels of Ordered Mesoporous Silica Constructed by a Pillar[5]arene-Based Host-Guest System
| Autor: | Fei Zhu, Ming Cheng, Siyun Zhang, Weiwei Xu, Manivannan Kalavathi Dhinakaran, Haibing Li |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Materials science
Pillar Enantioselective synthesis Nanotechnology 02 engineering and technology Mesoporous silica 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Chiral resolution 0104 chemical sciences General Materials Science 0210 nano-technology Selectivity Reusability |
| Zdroj: | ACS applied materialsinterfaces. 13(23) |
| ISSN: | 1944-8252 |
| Popis: | The separation of racemic compounds by chiral nanochannels has attracted extensive attention. However, the fabrication of high-performance chiral nanochannels is still a challenge owing to the difficulty in magnifying the weak chiral interaction to macroscopic properties of materials. Herein, by introducing a l-alanine-pillar[5]arene host to achiral ordered mesoporous silica (OMS), chiral OMS nanochannels were fabricated, which exhibited excellent selectivity (ee value up to 90.2%) to separate racemic drugs with promising reusability and stability. Besides, it was identified that enantioselective separation took place through a molecular-recognition-adsorbed transport mechanism. This work highlights the great potential of chiral OMS nanochannels as a platform for enantioselective separation. |
| Databáze: | OpenAIRE |
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