Cardiac resynchronization therapy via left bundle branch pacing vs. optimized biventricular pacing with adaptive algorithm in heart failure with left bundle branch block: a prospective, multi-centre, observational study
| Autor: | Jingfeng Wang, Xianxian Zhao, Yixiu Liang, Guosheng Fu, Xia Sheng, Junbo Ge, Kenneth A. Ellenbogen, Shengmei Qin, Xueying Chen, Zhongkai Wang, Yangang Su, Zhaohui Qiu, Yang Ye, Wei Wang, Haiyan Chen, Qinchun Jin, Jin Bai, Feng Gao |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Bundle of His
medicine.medical_specialty medicine.medical_treatment Bundle-Branch Block Cardiac resynchronization therapy Ventricular Function Left Cardiac Resynchronization Therapy Electrocardiography QRS complex Physiology (medical) Internal medicine Left bundle branch medicine Humans Prospective Studies Multi centre Heart Failure Ejection fraction Left bundle branch block business.industry Stroke Volume medicine.disease Treatment Outcome Heart failure Cardiology Implant Cardiology and Cardiovascular Medicine business Algorithms |
| Zdroj: | EP Europace. 24:807-816 |
| ISSN: | 1532-2092 1099-5129 |
| Popis: | Aims The purpose of our study was to evaluate the feasibility and efficacy of cardiac resynchronization therapy (CRT) via left bundle branch pacing (LBBP-CRT) compared with optimized biventricular pacing (BVP) with adaptive algorithm (BVP-aCRT) in heart failure with reduced left ventricular ejection fraction ≤35% (HFrEF) and left bundle branch block (LBBB). Methods and results One hundred patients with HFrEF and LBBB undergoing CRT were prospectively enrolled in a non-randomized fashion and divided into two groups (LBBP-CRT, n = 49; BVP-aCRT, n = 51) in four centres. Implant characteristics and echocardiographic parameters were accessed at baseline and during 6-month and 1-year follow-up. The success rate for LBBP-CRT and BVP-aCRT was 98.00% and 91.07%. Fused LBBP had the greatest reduced QRS duration compared to BVP-aCRT (126.54 ± 11.67 vs. 102.61 ± 9.66 ms, P Conclusions The feasibility and efficacy of LBBP-CRT demonstrated better electromechanical resynchronization and higher clinical and echocardiographic response, especially higher super-response than BVP-aCRT in HFrEF with LBBB. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|