Gut Microbiota Alterations from Three-Strain Yogurt Formulation Treatments in Slow-Transit Constipation
| Autor: | Yi-Yong Luo, Xiao-Ran Li, He-Ming Zhang, En Yang, Xiao-Dan Tang, Chen-Jian Liu, Le Zhang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Microbiology (medical)
chemistry.chemical_classification Constipation biology Strain (chemistry) Article Subject Fatty acid food and beverages Infectious and parasitic diseases RC109-216 Gut flora biology.organism_classification Microbiology QR1-502 Acetic acid chemistry.chemical_compound Infectious Diseases chemistry medicine Composition (visual arts) Food science Slow transit constipation medicine.symptom Feces Research Article |
| Zdroj: | The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien des Maladies Infectieuses et de la Microbiologie Médicale Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 2020 (2020) |
| ISSN: | 1712-9532 |
| DOI: | 10.1155/2020/4583973 |
| Popis: | The objective of this study was to evaluate the effects of a three-strain yogurt formulation in slow-transit constipation (STC) patients. Each individual in both treatment groups consumed 250 mL of the formulated yogurt daily for a week (7 days), and fecal samples were collected for gut microbiota and short-chain fatty acid (SCFA) analyses. A significant increase in the defection frequency (p<0.001) and bacterial diversity (p=0.027) at the 100% sequence homology level and a decrease in the concentrations of acetic acid (p=0.014), propionic acid (p=0.019), and butanoic acid (p=0.005) were observed after the STC patients consumed three-strain yogurt formulation. In addition, the consumption of the three-strain yogurt formulation significantly altered the composition of the intestinal bacteria in the STC patients. The relative abundances of 23 genera in the top dominating genera were altered significantly after the STC patients consumed the yogurt. In summary, the consumption of 250 mL day− the three-strain yogurt formulation described in this study can play a role in improving the symptoms of STC. |
| Databáze: | OpenAIRE |
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