Molecular epidemiological characteristics of Brucella spp. isolated from human and animal brucellosis
| Autor: | Tülin Güven Gökmen, Süleyman Aslan, Melda Meral, Togrul Nagiyev, Akgün Yaman, Pınar Etiz, Fatih Köksal |
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| Přispěvatelé: | Çukurova Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
General Veterinary biology Animal life Transmission (medicine) MLVA Surveillance Methods Brucellosis Brucella PFGE Multiple Loci VNTR Analysis medicine.disease biology.organism_classification bacterial infections and mycoses Virology Molecular surveillance Epidemiology Pulsed-field gel electrophoresis medicine Animal Science and Zoology |
| Popis: | WOS: 000466333800022 Brucellosis is the most common zoonotic disease in the Mediterranean region where Turkey is located. Therefore, particularly in this region, it is crucial to follow molecular surveillance methods for the control and eradication of this disease agent, which threatens both human and animal life. We have conducted a molecular-based surveillance study for detecting the origin of the possible reservoir in human brucellosis and transmission of Brucella spp. between humans and ruminants. For the detection of clonal relationships, we isolated Brucella spp. from human and ruminants diagnosed with brucellosis and evaluated them by PFGE and MLVA methods. We found 10 subclusters in PFGE and 22 subclusters in MLVA-16. Human and ruminant isolates were found to co-exist in MLVA-16-m1 and PFGE-a8, a9, a10 subcluster by both methods. In conclusion, the results revealed that these subcluster isolates that co-exist some ruminant and human isolates can be more effective in infecting humans. Cukurova University Scientific Research FundCukurova University [TF2013D2] This research was financially supported by Cukurova University Scientific Research Fund (Project no: TF2013D2). |
| Databáze: | OpenAIRE |
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