Small-molecule based musculoskeletal regenerative engineering
| Autor: | Tao Jiang, Cato T. Laurencin, Keith A. Gagnon, Clarke Nelson, Kevin W.-H. Lo |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
business.industry
Cartilage Bioactive molecules Regeneration (biology) Bioengineering Anatomy Regenerative Medicine Bioinformatics Regenerative medicine Article Musculoskeletal Abnormalities medicine.anatomical_structure Drug Discovery medicine Musculoskeletal tissue Musculoskeletal Diseases business Biotechnology |
| Zdroj: | Trends in Biotechnology. 32:74-81 |
| ISSN: | 0167-7799 |
| DOI: | 10.1016/j.tibtech.2013.12.002 |
| Popis: | Clinicians and scientists working in the field of regenerative engineering are actively investigating a wide range of methods to promote musculoskeletal tissue regeneration. Small molecule-mediated tissue regeneration is emerging as a promising strategy for regenerating various musculoskeletal tissues and a large number of small molecule compounds have been recently discovered as potential bioactive molecules for musculoskeletal tissue repair and regeneration. In this review, we summarize the recent literature encompassing the past four years in the area of small bioactive molecule for promoting repair and regeneration of various musculoskeletal tissues including bone, muscle, cartilage, tendon, and nerve. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect