Intravascular Ultrasound Validation of Contemporary Angiographic Scores Evaluating the Severity of Calcification in Peripheral Arteries
| Autor: | Da Yin, Akiko Maehara, Thomas Davis, Joseph J. Ricotta, William A. Gray, Mitsuaki Matsumura, Malcolm T. Foster, Gary S. Mintz, Venkatesh G. Ramaiah, Thomas Shimshak |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Arterial disease 030204 cardiovascular system & hematology Severity of Illness Index 03 medical and health sciences Peripheral Arterial Disease 0302 clinical medicine Predictive Value of Tests Intravascular ultrasound medicine Humans Radiology Nuclear Medicine and imaging 030212 general & internal medicine Prospective Studies Vascular Calcification Ultrasonography Interventional Aged medicine.diagnostic_test business.industry Angiography Reproducibility of Results Gold standard (test) medicine.disease Peripheral Arterial calcification Radiographic Image Interpretation Computer-Assisted Surgery Female Radiology Cardiology and Cardiovascular Medicine business Calcification |
| Zdroj: | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 24(4) |
| ISSN: | 1545-1550 |
| Popis: | To validate 3 angiographic scoring systems for peripheral artery calcification using intravascular ultrasound (IVUS) as the gold standard.The study employed preprocedure angiography and IVUS data from 47 patients (median age 72 years; 34 men) in the 55-patient JetStream G3 Calcium Study ( ClinicalTrials.gov identifier NCT01273623) to validate the 3 angiographic scoring systems [Peripheral Academic Research Consortium (PARC), Peripheral Arterial Calcium Scoring System (PACSS), and the DEFINITIVE CaIVUS detected calcium in 44/47 (93.6%) lesions, and angiography detected calcium in 26/47 (55.3%) lesions (p0.001). The sensitivity, specificity, positive predictive value, and negative predictive value of angiography relative to IVUS were 59%, 100%, 100%, and 14%, respectively. With increasing severity of angiographic calcium, there was a stepwise increase in the prevalence of IVUS superficial calcium and the maximum arc and length of superficial calcium. Using PARC criteria, with increasing severity of calcification, IVUS maximum calcium arc increased from 120° for none to 305° for severe (p0.001); the length of calcium increased from 7 to 68 mm (p0.001). Though a similar trend was seen in IVUS superficial calcium, it was not observed in IVUS deep calcium. Similar observations were seen when using the PACSS and DEFINITIVE CaIVUS confirmed that the PARC, PACSS, and DEFINITIVE Ca |
| Databáze: | OpenAIRE |
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