Arterial evaluation of systemic sclerosis patients with Doppler ultrasound: What did we find?

Autor:	Eren Erken, Suade Özlem Badak, Hülya Binokay, Esra Kayacan Erdoğan, Bozkurt Gulek
Rok vydání:	2021
Předmět:	Adult Male medicine.medical_specialty Carotid arteries Cardiovascular risk factors Disease Carotid Intima-Media Thickness 03 medical and health sciences 0302 clinical medicine Rheumatology Predictive Value of Tests Risk Factors Internal medicine medicine Humans cardiovascular diseases 030212 general & internal medicine Ultrasonography Doppler Color Prospective cohort study Aged Macrovascular disease 030203 arthritis & rheumatology Scleroderma Systemic business.industry Arteries Middle Aged medicine.disease Arterial occlusion Peripheral Carotid Arteries Cross-Sectional Studies Microvessels cardiovascular system Cardiology Female Doppler ultrasound Tunica Intima Tunica Media business
Zdroj:	International Journal of Rheumatic Diseases. 24:954-962
ISSN:	1756-185X 1756-1841
Popis:	AIM The aim of this study was to detect macrovascular findings in systemic sclerosis (SSc) by means of color Doppler ultrasonography (CDUS) and to evaluate the relationship between the laboratory and clinical findings in the setting of the disease. METHODS This was a cross-sectional study. Eighty-eight patients were included in the study. CDUS examinations of the bilateral carotid, vertebral, and peripheral arteries were performed. The presence of macrovascular involvement was investigated and recorded, and its relationships with the clinical, laboratory, and cardiovascular risk factors were evaluated. RESULTS An atheromatous plaque was found in 67.7% of the 1936 arteries examined by CDUS. Of these 1936 arteries, 37.4% demonstrated a narrowing of the intraluminal diameter. On the other hand, the carotid intima-media thickness (CIMT) was found to have increased in 55.7% of the patients. This increase was found to be statistically correlated with disease duration, the modified Rodnan Skin Thickness Score, and the Medsger Disease Activity Score. But no relation existed with the disease subtype, age, or cardiovascular risk factors. Arterial occlusion was detected in 10 patients. An association was found between the CIMT values and arterial occlusion. CONCLUSIONS In this study, we examined the arteries by means of CDUS, and we detected structural alterations in the peripheral and carotid arteries. We witnessed that these macrovascular changes had a close association with certain features of SSc. We think there is a need for broader prospective studies in order to evaluate the contribution of these factors to the macrovascular changes stated in the article.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75d8e04a56f1e63fa04f99fd6b97dcd https://doi.org/10.1111/1756-185x.14158 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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