Incidence and risk factors for calcification after dextranomer/hyaluronic acid (Dx/HA) copolymer injection for vesicoureteral reflux
| Autor: | Andrea Soria-Gondek, Xavier Tarrado-Castellarnau, Sonia Pérez-Bertólez, Alba Martín-Lluís, L. García-Aparicio, Oriol Martín-Solé |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Dextranomer/hyaluronic acid Urology 030232 urology & nephrology Asymptomatic Vesicoureteral reflux Risk factors 03 medical and health sciences 0302 clinical medicine Risk Factors 030225 pediatrics medicine Humans Clinical significance Hyaluronic Acid Child Survival analysis Vesico-Ureteral Reflux business.industry Incidence (epidemiology) Incidence Dextrans Implant calcification medicine.disease Surgery Child Preschool Pediatrics Perinatology and Child Health Dextranomer Implant medicine.symptom business medicine.drug Calcification |
| Zdroj: | JOURNAL OF PEDIATRIC UROLOGY r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu Fundació Sant Joan de Déu r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu instname |
| ISSN: | 1477-5131 1873-4898 |
| Popis: | INTRODUCTION: Since the first case of dextranomer/hyaluronic acid (Dx/HA) implant calcification in 2008, concern about the long-term sequelae of Dx/HA injection has been growing. According to previous reports, the incidence of Dx/HA calcification 4 years after injection would be around 2%. AIM: The primary aim was to estimate the incidence of Dx/HA implant calcification after endoscopic treatment of vesicoureteral reflux in pediatric patients. Secondary objectives were to establish risk factors and to perform a survival analysis after Dx/HA injection. STUDY DESIGN: Patients undergoing Dx/HA endoscopic injection from 2007 to 2014 were prospectively registered. The database included clinical, surgical and radiological outcomes. Patients that showed Dx/HA implant calcification during follow-up were compared to those who did not. Univariable and survival statistical analyses were performed. RESULTS: 30 implants calcified over 355 ureters endoscopically treated. Age at first treatment was lower in patients with implant calcification (2.4 ± 1.3 years vs 3.6 ± 2.5 years; p |
| Databáze: | OpenAIRE |
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