Nosocomial person-to-person transmission of severe fever with thrombocytopenia syndrome
| Autor: | Yun Kwon Kim, In Young Jung, Won Suk Choi, Young Uh, Eunbyeol Wang, Jun Yong Choi, Won-Ja Lee, Sun Whan Park, Jung-Sung Kim, Hwi Young Kim |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Pediatrics medicine.medical_specialty Health Personnel health care facilities manpower and services education 030106 microbiology 03 medical and health sciences 0302 clinical medicine Occupational Exposure Epidemiology Disease Transmission Infectious medicine Humans Infection transmission 030212 general & internal medicine Personal Protective Equipment Personal protective equipment Infection Control Transmission (medicine) business.industry virus diseases General Medicine Middle Aged medicine.disease Bloody Severe fever with thrombocytopenia syndrome Phlebotomus Fever Infectious Diseases Universal precautions Female business Severe fever with thrombocytopenia syndrome virus |
| Zdroj: | Clinical Microbiology and Infection. 25:633.e1-633.e4 |
| ISSN: | 1198-743X |
| DOI: | 10.1016/j.cmi.2019.01.006 |
| Popis: | Objectives This study is an epidemiologic investigation of nosocomial severe fever with thrombocytopenia syndrome virus (SFTSV) transmission among healthcare workers (HCWs) after contact with an index patient. The aim of this study was to determine whether exposure to blood or bloody respiratory secretion is associated with human-to-human transmission of SFTSV. Methods Eleven days after the index patient died, two HCWs who had close exposure to the patient presented with typical symptoms of SFTS. An epidemiological investigation was conducted on all 25 HCWs who had been in close contact with the index patient. Clinical and laboratory data were collected, and transmission rate before and after the index patient had haemorrhagic manifestations was analysed. Results Among 25 HCWs who had direct contact with the index patient, five HCWs were confirmed to have SFTS. All five HCWs had contact to blood or bloody respiratory secretions of the index patient without adequate use of personal protective equipment (PPE). No HCW with contact before haemorrhagic manifestations of the index patient contracted SFTS. Overall, the transmission rate was higher for HCWs who had contact after the index patient had haemorrhagic manifestations (33.3%, five of 15 HCWs, vs. 0%, zero of ten HCWs, p 0.041). Conclusions In HCWs who are inadequately protected, person-to-person transmission of SFTSV may be associated with contact with blood or bloody respiratory secretions. Therefore, universal precaution and full PPE is highly recommended for protection against SFTSV when there are signs of bleeding. |
| Databáze: | OpenAIRE |
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