Combined computed tomography-guided radiofrequency ablation and brachytherapy in a child with multiple recurrences of Wilms' tumor
| Autor: | Mohamedyakub A Puthawala, Gene A. Cardarelli, Sachin Gandhi, Damian E. Dupuy, Sandra J Meech, William S. Ferguson |
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| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
Percutaneous Palliative treatment Radiofrequency ablation medicine.medical_treatment Biopsy Brachytherapy Computed tomography Wilms Tumor law.invention law medicine Humans Child Chemotherapy medicine.diagnostic_test business.industry Wilms' tumor Hematology medicine.disease Kidney Neoplasms Leukemia Oncology Pediatrics Perinatology and Child Health Female Radiology Neoplasm Recurrence Local business Tomography X-Ray Computed |
| Zdroj: | Journal of pediatric hematology/oncology. 27(7) |
| ISSN: | 1077-4114 |
| Popis: | Background: Treatment of relapsed Wilms' tumor remains a challenge. We describe a case of an 11-year-old girl with multiply relapsed Wilms' tumor in whom combined percutaneous computed tomography (CT)-guided radiofrequency ablation and brachytherapy directed at a retroperitoneal tumor mass resulted in pain palliation and local tumor control. Observations: Over the course of few weeks, her requirement for narcotic pain medications dramatically decreased. A contrast-enhanced CT scan obtained at 8 months after the procedure showed no evidence for local tumor recurrence. However, she subsequently developed myelodysplasia with evolution into leukemia, presumably secondary to chemotherapy, and died 9.5 months after the procedure. Conclusion: Combined CT-guided radiofrequency ablation and brachytherapy is a promising new minimally invasive palliative treatment of recurrent Wilms' tumor. |
| Databáze: | OpenAIRE |
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