Risk of invasive breast cancer after lobular intra-epithelial neoplasia: Review of the literature
| Autor: | Laurence Salomon, Sarah Delaney, Y Ansquer, Rémy Salmon, Bruno Carbonne, P Santulli |
|---|---|
| Přispěvatelé: | Université Pierre et Marie Curie - Paris 6 (UPMC), Université Paris Diderot - Paris 7 (UPD7), Institut Curie/ Departement de chirurgie/ 26 rue d'Ulm/ 75005 Paris, Departement de chirurgie [Institut Curie], Institut Curie [Paris] |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Oncology
medicine.medical_specialty PubMed Both breasts review Breast Neoplasms Risk Assessment atypical lobular hyperplasia 03 medical and health sciences 0302 clinical medicine Breast cancer breast cancer Risk Factors Internal medicine medicine Carcinoma Humans Neoplasm Invasiveness Contralateral breast Risk factor skin and connective tissue diseases lobular carcinoma in situ 030304 developmental biology Gynecology 0303 health sciences Average risk business.industry Carcinoma Ductal Breast Neoplasms Second Primary General Medicine medicine.disease 3. Good health Carcinoma Lobular Carcinoma Intraductal Noninfiltrating 030220 oncology & carcinogenesis lobular intraepithelial neoplasia Surgery Female Breast disease France Risk assessment business |
| Zdroj: | EJSO-European Journal of Surgical Oncology EJSO-European Journal of Surgical Oncology, WB Saunders, 2010, 36 (7), pp.604. ⟨10.1016/j.ejso.2010.05.019⟩ EJSO-European Journal of Surgical Oncology, 2010, 36 (7), pp.604. ⟨10.1016/j.ejso.2010.05.019⟩ |
| ISSN: | 0748-7983 |
| DOI: | 10.1016/j.ejso.2010.05.019⟩ |
| Popis: | Objective Lobular intra-epithelial neoplasia (LIN) is a rare breast disease that has been regarded alternately as a risk factor for invasive breast cancer in both breasts or a true breast cancer precursor. The controversy is largely dependent on the estimation of the IBC (Invasive Breast Cancer) risk after LIN; however a systematic review of the published data has not been previously performed. We aimed to review the IBC after LIN and the characteristics of those cancers. Methods A PubMed search was performed to identify the published articles in English addressing the breast cancer risk after LIN. Results There was a wide range in the figures estimating the risk of the breast cancer among the 22 studies that form the basis of this review. The cumulative average risk of invasive breast cancer (IBC) was 8.7% (range 0–33). It was 4.7% (range 0–25) for the ipsilateral and 4.2% (range 0–16) for the contralateral breast. 52% of the breast cancers occurred more than 10 years after the initial LIN. A lobular histotype was present in 30% (range 0–67%) of all IBC. Conclusions LIN should be considered both as a risk factor (low and similar level of IBC risk for both breasts, long delay between LIN and IBC) and a precursor for IBC (over-representation of lobular histotype). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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