The 2016 Assisi Think Tank Meeting on breast cancer: white paper

Autor: Vincenzo Valentini, Cynthia Aristei, Philip Poortmans, Charlotte E. Coles, Birgitte Vrou Offersen, Maria Cristina Leonardi, Giovanni Frezza, Céline Bourgier, Orit Kaidar-Person, Meritxell Arenas
Přispěvatelé: Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Oncology
Research design
Cancer Research
medicine.medical_specialty
medicine.medical_treatment
[SDV.CAN]Life Sciences [q-bio]/Cancer
Computer-assisted web interviewing
Systemic therapy
Breast cancer
Breast reconstruction
Post-mastectomy radiation therapy
Primary systemic therapy
Radiation therapy
Regional lymph node treatment
03 medical and health sciences
0302 clinical medicine
White paper
Internal medicine
Medicine
Medical physics
030212 general & internal medicine
Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA
MESH: Humans
business.industry
medicine.disease
Women's cancers Radboud Institute for Health Sciences [Radboudumc 17]
3. Good health
Clinical trial
030220 oncology & carcinogenesis
business
MESH: Female
MESH: Breast Neoplasms
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Zdroj: Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, Springer Verlag, 2016, 160 (2), pp.211-221. ⟨10.1007/s10549-016-3998-2⟩
Aristei, C, Kaidar-Person, O, Arenas, M, Coles, C, Offersen, B V, Bourgier, C, Frezza, G, Leonardi, M C, Valentini, V & Poortmans, P M P 2016, ' The 2016 Assisi Think Tank Meeting on breast cancer: white paper ', Breast Cancer Research and Treatment, vol. 160, no. 2, pp. 211-221 . https://doi.org/10.1007/s10549-016-3998-2
Breast Cancer Research and Treatment, 160, 2, pp. 211-221
Breast Cancer Research and Treatment, 160, 211-221
ISSN: 0167-6806
1573-7217
Popis: Item does not contain fulltext PURPOSE: To identify weak points in daily routine use of radiation therapy (RT) for non-metastatic breast cancer patients, particularly when data are lacking or equivocal, a "think tank" of experts met in Assisi. METHODS: Before the meeting, controversial issues on non-metastatic breast cancer were identified and reviewed, and clinical practice investigated by means of an online questionnaire. During the 3-day meeting, topics were discussed in-depth with attendees and potential sponsors that are involved in breast cancer treatment. RESULTS: Three issues were identified as needing further investigation: (1) Regional lymph node treatment in early-stage breast cancer; (2) Combined post-mastectomy RT and breast reconstruction; (3) RT in patients treated with primary systemic therapy. Future research proposals included the following: (1) Participating in appropriately selected on-going clinical trials; (2) Designing new randomized controlled clinical trials and prospective population cohort studies; (3) Setting-up large database(s) to generate predictive response models and detect biomarkers for tailored loco-regional treatments. CONCLUSIONS: It is hoped that the ATTM findings, as described in the present white paper, will stimulate a new generation of radiation oncologists to focus on research in these areas, and that the white paper will become a tool for multidisciplinary groups to help them design research proposals and strategies.
Databáze: OpenAIRE
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