Diagnóstico citogenético e molecular da anemia de Fanconi

Autor:	Carmen Silvia Bertuzzo, Maristela Zocca, Carmen Silvia Passos Lima, Davi E. A. Rodriguez, Gustavo Jacob Lourenço
Jazyk:	angličtina
Rok vydání:	2003
Předmět:	FANCC Gene Hematology Biology medicine.disease Molecular biology law.invention chemistry.chemical_compound chemistry Fanconi anemia law hemic and lymphatic diseases Mutation (genetic algorithm) medicine DNA Polymerase chain reaction
Zdroj:	Revista Brasileira de Hematologia e Hemoterapia v.25 n.3 2003 Revista brasileira de hematologia e hemoterapia Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC) instacron:ABHHTC Revista Brasileira de Hematologia e Hemoterapia, Volume: 25, Issue: 3, Pages: 191-192, Published: 2003
Popis:	Polymerase chain reaction and restrictionendonuclease digestion for detection of IVS4+4A?T mutationof the FANCC gene. Ethidium bromide-stained 8%polyacrylamide gel showing fragments of 108 bpcorresponding to the absence of the mutation and fragmentsof 131 bp corresponding to the presence of the mutation.Lane 1 shows the DNA size markers Ladder 100 bp. Lane 2shows the result from an individual with homozygousmutation (Fanconi anaemia) and lanes 3, 4 and 5 show theresults from heterozygous individuals of the same family
Databáze:	OpenAIRE
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