Rotavirus gastroenteritis in Latin America: A hospital-based study in children under 3years of age
| Autor: | Doris Maribel Rivera-Medina, Rodrigo Vergara, F. Raúl Velázquez, Belén Salinas, Yolanda Cervantes, Luis Rivera, Eduardo Ortega-Barria, Hector Abate, Elias Jimenez, Ricardo Rüttimann, Xavier Sáez-Llorens, Pilar Rubio, Mercedes Macias-Parra, Thomas Breuer, Alexandre da Costa Linhares |
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| Rok vydání: | 2012 |
| Předmět: |
Gynecology
medicine.medical_specialty Pediatrics Rotav?rus business.industry Immunology Gastroenterite Public Health Environmental and Occupational Health Vacinas contra Rotavirus Rotavirus Infections Rotavirus gastroenteritis Microbiology Diarrhoea Gastroenteritis Hospital based study Rotavirus infections Latin America Infectious Diseases Cost of illness Medicine Infec??es por Rotavirus Diarreia business |
| Zdroj: | Repositório Digital do Instituto Evandro Chagas (Patuá) Instituto Evandro Chagas (IEC) instacron:IEC |
| ISSN: | 1879-4378 |
| DOI: | 10.1016/j.trivac.2012.07.002 |
| Popis: | GlaxoSmithKline (GSK) Biologicals was the funding source and was involved in all stages of the study conduct and analysis. GSK Biologicals also funded all costs associated with the development and the publishing of the present manuscript. Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Bel?m, PA, Brasil. Instituto Nacional de Pediatr?a. M?xico D.F., Mexico. Hospital del Ni?o. Panama City, Panama. Universidad de Valpara?so. Escuela de Medicina. Valpara?so, Chile. Instituto Costarricense de Investigaciones Cl?nicas. Urbanizaci?n de Los Arboles La Uruca. San Jos?, Costa Rica. Instituto Mexicano del Seguro Social. CMN-SXX. Pediatrics Hospital. Medical Research Unit on Infectious Diseases. Mexico City, Mexico. GlaxoSmithKline Biologicals M?xico. M?xico D.F., M?xico. Hospital Dr. Humberto Notti. Villa Nueva de Guaymall?n, Mendoza, Argentina. Hospital Maternidad Nuestra Sra de la Altagracia. Santo Domingo, D.N., Dominican Republic. GlaxoSmithKline Biologicals Argentina. Victoria, Buenos Aires, Argentina. Organizaci?n para el Desarrollo y la Investigaci?n Salud en Honduras. Colonia Humuya, Sendero Pastizal, Tegucigalpa, Honduras. Ciudad Hospitalaria Dr. Enrique Tejera. Hospital de Ni?os Dr. Jorge Lizarraga. Carabobo, Valencia, Venezuela. Fundaci?n para el Avance de la Investigaci?n Cl?nica y Translacional. Consultores M?dicos Am?rica. V?a Espa?a, Carrasquilla, Panama. GlaxoSmithKline Biologicals Costa Rica. San Jose, Costa Rica. GlaxoSmithKline Biologicals Belgium. Rixensart, Belgium. Rotavirus is the leading cause of severe diarrheal disease and dehydration in infants in both developed and developing countries. Vaccines have recently been developed, but detailed epidemiological information, which is needed for decisions about how and where to introduce vaccination, was lacking for many Latin American countries. The primary objective of this study was to measure the incidence and disease burden of rotavirus in young children presenting to Latin American hospitals with gastroenteritis. In addition it allowed to setting up the methodology to further conduct a large phase III trial with a rotavirus vaccine in the region. This was a prospective, multi-center surveillance study of gastroenteritis in children |
| Databáze: | OpenAIRE |
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