Supramolecular organization of bacterial aerobic respiratory chains: From cells and back
| Autor: | Miguel Teixeira, Ana M.P. Melo |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Supramolecular chemistry Respiratory chain Biophysics Biology Biochemistry Cell membrane Electron Transport 03 medical and health sciences Bacterial Proteins medicine Bioenergetic systems Bacteria Chemiosmosis Cell Membrane Proton-Motive Force Cell Biology biology.organism_classification Electron transport chain Aerobiosis 030104 developmental biology medicine.anatomical_structure Electron Transport Chain Complex Proteins Archaea |
| Zdroj: | Biochimica et biophysica acta. 1857(3) |
| ISSN: | 0006-3002 |
| Popis: | Aerobic respiratory chains from all life kingdoms are composed by several complexes that have been deeply characterized in their isolated form. These membranous complexes link the oxidation of reducing substrates to the reduction of molecular oxygen, in a process that conserves energy by ion translocation between both sides of the mitochondrial or prokaryotic cytoplasmatic membranes. In recent years there has been increasing evidence that those complexes are organized as supramolecular structures, the so-called supercomplexes and respirasomes, being available for eukaryotes strong data namely obtained by electron microscopy and single particle analysis. A parallel study has been developed for prokaryotes, based on blue native gels and mass spectrometry analysis, showing that in these more simple unicellular organisms such supercomplexes also exist, involving not only typical aerobic-respiration associated complexes, but also anaerobic-linked enzymes. After a short overview of the data on eukaryotic supercomplexes, we will analyse comprehensively the different types of prokaryotic aerobic respiratory supercomplexes that have been thus far suggested, in both bacteria and archaea. This article is part of a Special Issue entitled Organization and dynamics of bioenergetic systems in bacteria, edited by Prof Conrad Mullineaux. |
| Databáze: | OpenAIRE |
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