Benzoic Acid Combined with Essential Oils Can Be an Alternative to the Use of Antibiotic Growth Promoters for Piglets Challenged with E. coli F4
| Autor: | Márvio Lobão Teixeira de Abreu, Letícia Mendonça Rodrigues, Vinícius de Souza Cantarelli, Rony Antonio Ferreira, Dino Garcez, Túlio Otávio de Araújo Lima Neto, Cesar Augusto Pospissil Garbossa, Claudia Cassimira da Silva Martins, Laya Kannan Silva Alves |
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| Rok vydání: | 2020 |
| Předmět: |
animal diseases
Population Randomized block design Weanling 03 medical and health sciences chemistry.chemical_compound Animal science lcsh:Zoology pig nutrition lcsh:QL1-991 bacteria education Thymol 030304 developmental biology Benzoic acid organic acid chemistry.chemical_classification stress physiology 0303 health sciences education.field_of_study lcsh:Veterinary medicine General Veterinary weaning microbiology 0402 animal and dairy science 04 agricultural and veterinary sciences bacterial infections and mycoses ANTIBIÓTICOS 040201 dairy & animal science Eugenol chemistry Piperine lcsh:SF600-1100 Animal Science and Zoology Organic acid |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP Animals Volume 10 Issue 11 Animals, Vol 10, Iss 1978, p 1978 (2020) |
| ISSN: | 2076-2615 |
| Popis: | Benzoic acid (BA) and essential oils (EOs) (thymol, 2-methoxyphenol, eugenol, piperine, and curcumin) are being studied to minimize the impairment of gastrointestinal functions in weanling piglets. This study evaluates the effects of combining BA and EO on the performance and intestinal health of piglets challenged with E. coli F4 (1 mL, 106 CFU/mL). In total, 270 weaned piglets were used in a randomized block design with six treatments: positive control, with 40 mg/kg colistin (PC) negative control, without the growth promoter (NC) negative control +5 g/kg benzoic acid (BA) negative control +2 g/kg combination of BA+EO (BA+EO2) negative control +3 g/kg combination of BA+EO (BA+EO3) negative control +4 g/kg combination of BA+EO (BA+EO4). BA+EO3 presented a greater average daily gain (ADG) (p = 0.0013) and better feed-to-gain ratio (p = 0.0138), compared to NC, from 21 to 35 days age. For the total period, BA, BA+EO3, and BA+EO4 were similar to PC and superior to NC for ADG (p = 0.0002) and final body weight (BW) (p = 0.0002). No difference (p > 0.05) was verified for diarrhea, microbial population, production of volatile fatty acids, pH, weight of organs, cellular proliferation, and cholecystokinin count. NC and BA+EO4 resulted in a higher villus height in the jejunum (p = 0.0120) compared to BA+EO3. The use of BA or the combination of BA and EO at 3 g/kg provides improved performance, aside from being an economically viable alternative to replace colistin. |
| Databáze: | OpenAIRE |
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