Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits
| Autor: | Felipe Jiménez-Aspee, Iris Catiana Zampini, Cristina Quispe, Cristina Theoduloz, Maria Del Pilar C. Soriano, Guillermo Schmeda-Hirschmann, María Rosa Alberto, María Inés Isla |
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| Rok vydání: | 2015 |
| Předmět: |
Cactaceae
medicine.drug_class Biotecnología Agropecuaria Lipoxygenase Anti-Inflammatory Agents Eulychnia acida Biology Positive correlation Antioxidants Anti-inflammatory ANTI-INFLAMMATORY CAPACITY Phenols Botany medicine Animals Humans Cyclooxygenase Inhibitors Lipoxygenase Inhibitors Chile Sheep Plant Extracts food and beverages Plant physiology EULYCHNIA ACIDA COPAO Recombinant Proteins Horticulture CIENCIAS AGRÍCOLAS Cyclooxygenase 2 Chemistry (miscellaneous) Fruit Biotecnología Agrícola y Biotecnología Alimentaria Cyclooxygenase 1 biology.protein Pulp (tooth) CACTACEAE Food Science |
| Zdroj: | Plant Foods for Human Nutrition. 70:135-140 |
| ISSN: | 1573-9104 0921-9668 |
| DOI: | 10.1007/s11130-015-0468-7 |
| Popis: | Copao (Eulychnia acida Phil., Cactaceae) is an endemic species occurring in northern Chile. The edible fruits of this plant are valued for its acidic and refreshing taste. Phenolic-enriched extracts from copao fruit pulp and epicarp, collected in the Elqui and Limari river valleys, were assessed by its in vitro ability to inhibit the pro-inflammatory enzymes lipoxygenase (LOX) and cyclooxygenases (COX-1 and COX-2). At 100 μg/mL, pulp extracts showed better effect towards LOX than epicarp extract, while COX-2 inhibition was observed for both epicarp and pulp samples. In general, the extracts were inactive towards COX-1. A positive correlation was observed between the anti-inflammatory activity and the main phenolic compounds found in this fruit. Copao fruits from the Limari valley, a main place of collection and commercialization, showed major activity, adding evidence on the possible health-beneficial effects of this native Chilean fruit. Fil: Jiménez Aspee, Felipe. Universidad de Talca; Chile Fil: Alberto, Maria Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina Fil: Quispe, Cristina. Universidad de Talca; Chile Fil: Caramantin Soriano, Maria del Pilar. Universidad de Talca; Chile Fil: Theoduloz, Cristina. Universidad de Talca; Chile Fil: Zampini, Iris Catiana. Universidad de Talca; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina Fil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina Fil: Schmeda Hirschmann, Guillermo. Universidad de Talca; Chile |
| Databáze: | OpenAIRE |
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