Anti-GBM Disease in Pregnancy: Acute Renal Failure Resolved After Plasma Exchange, Hemodialysis, and Steroids
| Autor: | Sufyan Abdul Mujeeb, Syed Hashmi, William Kern, Jordan Morton, Benjamin D. Cowley, Mohammed Muqeet Adnan |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Pediatrics Cyclophosphamide Epidemiology medicine.medical_treatment 030232 urology & nephrology Renal function 030204 cardiovascular system & hematology Abortion urologic and male genital diseases Article antiglomerular basement membrane disease 03 medical and health sciences 0302 clinical medicine medicine therapeutics Safety Risk Reliability and Quality Intensive care medicine Dialysis Pregnancy Fetus business.industry Acute kidney injury medicine.disease acute kidney injury Hemodialysis pregnancy business Safety Research glomerulonephritis medicine.drug |
| Zdroj: | Journal of Investigative Medicine High Impact Case Reports |
| ISSN: | 2324-7096 |
| Popis: | Antiglomerular basement membrane (GBM) disease presenting during pregnancy is uncommon. We present a case of a pregnant female who presented with acute renal failure requiring dialysis due to anti-GBM disease. She responded well to plasma exchange, high-dose steroids, and hemodialysis. Cyclophosphamide was discussed but not given at the patient’s request due to concerns for the well-being of the fetus. Unfortunately, she suffered a spontaneous abortion in her eighth week of pregnancy. Subsequently, she had progressive improvement in her renal function and became hemodialysis independent at 2 weeks after diagnosis. Her renal function returned to baseline 3 months after diagnosis. We present this case in detail and review the literature regarding anti-GBM disease in pregnancy. |
| Databáze: | OpenAIRE |
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