Comparative study of high sensitivity troponin T and heart-type fatty acid-binding protein in STEMI patients
| Autor: | Cholenhally Nanjappa Manjunath, Shaheena Banu, Syed Tanveer |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Acute coronary syndrome Ejection fraction Agricultural and Biological Sciences(all) business.industry Heart fatty acid binding protein Window period Chest pain Bioinformatics High Sensitivity Troponin T medicine.disease High sensitive-CRP Heart-type fatty acid binding protein Internal medicine Cardiology Medicine Original Article Myocardial infarction High sensitive-troponin T medicine.symptom General Agricultural and Biological Sciences business TIMI |
| Zdroj: | Saudi Journal of Biological Sciences. 22(1):56-61 |
| ISSN: | 1319-562X |
| DOI: | 10.1016/j.sjbs.2014.05.011 |
| Popis: | Aim and backgroundHeart-type fatty acid-binding proteins (H-FABP) which are detected within 2–3h of acute myocardial infarction are involved in uptake of free fatty acids in the myocardium. Our aim in the present study is to compare window periods of H-FABP to high sensitivity troponin T (hs-Trop T) in acute ST elevation myocardial infarction (STEMI).Methods160 STEMI diagnosed patient’s serum samples are analyzed for hs-Trop T and H-FABP. Different window periods of chest pain onset (6h) are compared with complications, in-hospital mortality and statistically analyzed.ResultsFrom 160 patients, 53 (33%) cases are presented in 6h respectively. Accordingly sensitivity of hs-Trop T was 92%, 94% and 97% while H-FABP was 75%, 88% and 84%, respectively. Overall sensitivity was 94% and 82% respectively. Statistically significant difference between mean hs-Trop T values with respect to window period 6h was 0.21, 0.35 and 0.80ng/ml respectively, p value |
| Databáze: | OpenAIRE |
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