Studies on the structure and physiology of salmon teleocalcin

Autor:	Graham F. Wagner, Henry G. Friesen
Rok vydání:	2013
Předmět:	Physiology chemistry.chemical_element General Medicine Aquatic Science Calcium Biology Biochemistry Epithelium Prolactin Residue (chemistry) medicine.anatomical_structure chemistry medicine Peptide sequence Homeostasis Function (biology) Hormone
Zdroj:	Fish physiology and biochemistry. 7(1-6)
ISSN:	0920-1742
Popis:	The structure and physiology of salmon teleocalcin, a Ca(+2) regulating hormone from the corpuscles of Stannius (CS) is reviewed. Teleocalcin is produced by the PAS+, type 1 cells in the CS. The hormone is a disulfide-linked homodimer, with a unique amino acid sequence and a carbohydrate moiety on residue 29. The teleocalcin monomer has a MW of 30 KD, whereas the pro-form of the monomer is 32 KD. The hormone is positively regulated by Ca(+2) and its function is to slow the active transport of Ca(+2) across the gill epithelium. In conjunction with prolactin, which stimulates Ca(+2) transport, teleocalcin is one of the major factors involved in Ca(+2) homeostasis in fish.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b718dce35e3dd6385c9f6e82175cd762 https://pubmed.ncbi.nlm.nih.gov/24221795 Zobrazit plný text záznamu Full text from SpringerLink