Neuropsychological outcome of infant heart transplant recipients
| Autor: | M. Catherin Freier, Kim R. Freeman, Marti Baum, Stephen Ashwal, Talin Babikian, Richard E. Chinnock, Leonard L. Bailey |
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| Rok vydání: | 2004 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Intelligence CBCL Neuropsychological Tests Hypoplastic left heart syndrome Borderline intellectual functioning Risk Factors medicine Humans Postoperative Period Child business.industry Neuropsychology Infant Newborn Wechsler Scales Wechsler Adult Intelligence Scale medicine.disease Transplantation El Niño Socioeconomic Factors Pediatrics Perinatology and Child Health Heart Transplantation Female business Psychosocial |
| Zdroj: | The Journal of pediatrics. 145(3) |
| ISSN: | 0022-3476 |
| Popis: | Objective To assess long-term neuropsychological outcomes of infant heart transplant recipients. Study design Fifty-five children (mean age, 6.4 years) with a primary diagnosis of hypoplastic left heart syndrome or other cardiac disorders participated in the study. Six areas of risk were assessed (birth; preoperative, intraoperative, and postoperative status; long-term medical complications; and socioeconomic factors). Neuropsychological evaluations included the following: Wechsler Scales of Intelligence, Wechsler Individual Achievement Test, Berry Visual Motor Integration Scale, Comprehensive Evaluation of Language Function, and Achenbach Child Behavioral Checklist. Results Intellectual functioning scores revealed a mean full-scale IQ of 81 ± 19. Intraoperative and postoperative variables (bypass time, hospital course, and lowest posttransplant pH), long-term medical complications (serious infections and posttransplant surgical procedures), and socioeconomic factors were associated with cognitive functioning. Visual-motor functioning was also related to bypass and total support time. Conclusions Long-term outcomes reveal low-average neuropsychological functioning and are related to intrasurgical-postsurgical, long-term medical, and socioeconomic factors. The neuropsychological and psychosocial functioning of infant heart transplant recipients will be important to address as they mature during adolescence and adulthood. |
| Databáze: | OpenAIRE |
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