Estimating the Burden of Leptospirosis among Febrile Subjects Aged below 20 Years in Kampong Cham Communities, Cambodia, 2007-2009
Autor: | Seiha Heng, Arnaud Tarantola, Rekol Huy, Touch Sok, Sopheak Hem, Florian Vogt, Sowath Ly, Mathieu Picardeau, Sovann Ly, Nima Asgari, Irene Votsi, Philippe Buchy, Simon Cauchemez, Bertrand Guillard |
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Přispěvatelé: | Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP), Modélisation mathématique des maladies infectieuses, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), London School of Hygiene and Tropical Medicine (LSHTM), World Health Organization [Phnom Penh] (WHO), Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Centre Collaborateur FAO/OMS pour l'épidémiologie de la leptospirose, Institut Pasteur [Paris], Centre National de Référence de la Leptospirose - National Reference Center Leptospirosis (CNR), Ministry of Health [Phnom Penh], National Center of Parasitology (CNM), National Malaria Center [Phnom Penh], This study was supported by the World Health Organization and the European Union and Pediatric Vaccine Dengue Initiative project (PDVI) from the International Vaccine Institute (IVI). Aside from coauthor NA who helped discuss the study results and edit the article, the funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP), Institut Pasteur du Cambodge-Réseau International des Instituts Pasteur ( RIIP ), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique ( CNRS ), London School of Hygiene and Tropical Medicine ( LSHTM ), World Health Organization [Phnom Penh] ( WHO ), World Health Organization, Centre National de Référence des Leptospires-Biologie des Spirochètes ( CNR-CC FAO/OMS ), Communicable Disease Department [Phnom Penh] ( CDC MOH ), Ministry of Health, National Center for Malaria Control, Parasitology and Entomology, Ministry of Health of Cambodgia, This study was supported by the World Health Organization and the European Union and Pediatric Vaccine Dengue Initiative project (PDVI) from the International Vaccine Institute (IVI). |
Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
MESH : Cambodia/epidemiology
Male Rural Population Pathology and Laboratory Medicine Biochemistry 0302 clinical medicine MESH : Immunoglobulin M/blood MESH : Child MESH: Rural Population [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases MESH: Child Chikungunya Enzyme-Linked Immunoassays lcsh:Science Child MESH : Dengue/epidemiology Leptospira education.field_of_study MESH : Antibodies Bacterial/blood MESH : Infant MESH: Leptospirosis Leptospirosis MESH: Infant MESH: Immunoglobulin M 3. Good health Bacterial Pathogens Veterinary Diseases Medical Microbiology Child Preschool medicine.medical_specialty 030106 microbiology Immunology MESH: Social Planning Microbiology 03 medical and health sciences Signs and Symptoms MESH : Adolescent MESH : Leptospirosis/blood Humans education Immunoassays Microbial Pathogens MESH: Adolescent MESH: Humans Bacteria Public health MESH : Humans lcsh:R MESH: Child Preschool Organisms Infant Biology and Life Sciences Proteins MESH: Adult Japanese encephalitis medicine.disease Tropical Diseases lcsh:Q Veterinary Science MESH: Female Demography 0301 basic medicine Bacterial Diseases Physiology lcsh:Medicine Fevers MESH: Dengue MESH : Child Preschool medicine.disease_cause Serology Dengue fever Dengue Geographical Locations [ SDV.MP ] Life Sciences [q-bio]/Microbiology and Parasitology Zoonoses Immune Physiology MESH: Antibodies Bacterial Medicine and Health Sciences MESH : Female Multidisciplinary Immune System Proteins biology MESH: Infant Newborn MESH : Adult Antibodies Bacterial Infectious Diseases Female Social Planning Pathogens Cambodia Research Article Neglected Tropical Diseases Adult MESH : Dengue/blood Asia Adolescent MESH : Male 030231 tropical medicine Population MESH : Infant Newborn Research and Analysis Methods Antibodies MESH : Social Planning Diagnostic Medicine medicine MESH : Leptospirosis/epidemiology business.industry MESH: Cambodia Infant Newborn biology.organism_classification MESH: Male MESH : Rural Population Immunoglobulin M People and Places Immunologic Techniques business |
Zdroj: | PLoS ONE PLoS ONE, Public Library of Science, 2016, 11 (4), pp.e0151555. ⟨10.1371/journal.pone.0151555⟩ PLoS ONE, Vol 11, Iss 4, p e0151555 (2016) PLoS ONE, 2016, 11 (4), pp.e0151555. ⟨10.1371/journal.pone.0151555⟩ PLoS ONE, Public Library of Science, 2016, 11 (4), pp.e0151555. 〈10.1371/journal.pone.0151555〉 |
ISSN: | 1932-6203 |
DOI: | 10.1371/journal.pone.0151555⟩ |
Popis: | International audience; BACKGROUND:Leptospirosis is an emerging but neglected public health challenge in the Asia/Pacific Region with an annual incidence estimated at 10-100 per 100,000 population. No accurate data, however, are available for at-risk rural Cambodian communities.METHOD:We conducted anonymous, unlinked testing for IgM antibodies to Leptospira spp. on paired sera of Cambodian patients |
Databáze: | OpenAIRE |
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