Estimating the Burden of Leptospirosis among Febrile Subjects Aged below 20 Years in Kampong Cham Communities, Cambodia, 2007-2009

Autor: Seiha Heng, Arnaud Tarantola, Rekol Huy, Touch Sok, Sopheak Hem, Florian Vogt, Sowath Ly, Mathieu Picardeau, Sovann Ly, Nima Asgari, Irene Votsi, Philippe Buchy, Simon Cauchemez, Bertrand Guillard
Přispěvatelé: Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP), Modélisation mathématique des maladies infectieuses, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), London School of Hygiene and Tropical Medicine (LSHTM), World Health Organization [Phnom Penh] (WHO), Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Centre Collaborateur FAO/OMS pour l'épidémiologie de la leptospirose, Institut Pasteur [Paris], Centre National de Référence de la Leptospirose - National Reference Center Leptospirosis (CNR), Ministry of Health [Phnom Penh], National Center of Parasitology (CNM), National Malaria Center [Phnom Penh], This study was supported by the World Health Organization and the European Union and Pediatric Vaccine Dengue Initiative project (PDVI) from the International Vaccine Institute (IVI). Aside from coauthor NA who helped discuss the study results and edit the article, the funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP), Institut Pasteur du Cambodge-Réseau International des Instituts Pasteur ( RIIP ), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique ( CNRS ), London School of Hygiene and Tropical Medicine ( LSHTM ), World Health Organization [Phnom Penh] ( WHO ), World Health Organization, Centre National de Référence des Leptospires-Biologie des Spirochètes ( CNR-CC FAO/OMS ), Communicable Disease Department [Phnom Penh] ( CDC MOH ), Ministry of Health, National Center for Malaria Control, Parasitology and Entomology, Ministry of Health of Cambodgia, This study was supported by the World Health Organization and the European Union and Pediatric Vaccine Dengue Initiative project (PDVI) from the International Vaccine Institute (IVI).
Jazyk: angličtina
Rok vydání: 2016
Předmět:
MESH : Cambodia/epidemiology
Male
Rural Population
Pathology and Laboratory Medicine
Biochemistry
0302 clinical medicine
MESH : Immunoglobulin M/blood
MESH : Child
MESH: Rural Population
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
MESH: Child
Chikungunya
Enzyme-Linked Immunoassays
lcsh:Science
Child
MESH : Dengue/epidemiology
Leptospira
education.field_of_study
MESH : Antibodies
Bacterial/blood

MESH : Infant
MESH: Leptospirosis
Leptospirosis
MESH: Infant
MESH: Immunoglobulin M
3. Good health
Bacterial Pathogens
Veterinary Diseases
Medical Microbiology
Child
Preschool

medicine.medical_specialty
030106 microbiology
Immunology
MESH: Social Planning
Microbiology
03 medical and health sciences
Signs and Symptoms
MESH : Adolescent
MESH : Leptospirosis/blood
Humans
education
Immunoassays
Microbial Pathogens
MESH: Adolescent
MESH: Humans
Bacteria
Public health
MESH : Humans
lcsh:R
MESH: Child
Preschool

Organisms
Infant
Biology and Life Sciences
Proteins
MESH: Adult
Japanese encephalitis
medicine.disease
Tropical Diseases
lcsh:Q
Veterinary Science
MESH: Female
Demography
0301 basic medicine
Bacterial Diseases
Physiology
lcsh:Medicine
Fevers
MESH: Dengue
MESH : Child
Preschool

medicine.disease_cause
Serology
Dengue fever
Dengue
Geographical Locations
[ SDV.MP ] Life Sciences [q-bio]/Microbiology and Parasitology
Zoonoses
Immune Physiology
MESH: Antibodies
Bacterial

Medicine and Health Sciences
MESH : Female
Multidisciplinary
Immune System Proteins
biology
MESH: Infant
Newborn

MESH : Adult
Antibodies
Bacterial

Infectious Diseases
Female
Social Planning
Pathogens
Cambodia
Research Article
Neglected Tropical Diseases
Adult
MESH : Dengue/blood
Asia
Adolescent
MESH : Male
030231 tropical medicine
Population
MESH : Infant
Newborn

Research and Analysis Methods
Antibodies
MESH : Social Planning
Diagnostic Medicine
medicine
MESH : Leptospirosis/epidemiology
business.industry
MESH: Cambodia
Infant
Newborn

biology.organism_classification
MESH: Male
MESH : Rural Population
Immunoglobulin M
People and Places
Immunologic Techniques
business
Zdroj: PLoS ONE
PLoS ONE, Public Library of Science, 2016, 11 (4), pp.e0151555. ⟨10.1371/journal.pone.0151555⟩
PLoS ONE, Vol 11, Iss 4, p e0151555 (2016)
PLoS ONE, 2016, 11 (4), pp.e0151555. ⟨10.1371/journal.pone.0151555⟩
PLoS ONE, Public Library of Science, 2016, 11 (4), pp.e0151555. 〈10.1371/journal.pone.0151555〉
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0151555⟩
Popis: International audience; BACKGROUND:Leptospirosis is an emerging but neglected public health challenge in the Asia/Pacific Region with an annual incidence estimated at 10-100 per 100,000 population. No accurate data, however, are available for at-risk rural Cambodian communities.METHOD:We conducted anonymous, unlinked testing for IgM antibodies to Leptospira spp. on paired sera of Cambodian patients
Databáze: OpenAIRE