Risk Factors for Preoperative Developmental Delay in Patients with Nonsyndromic Sagittal Craniosynostosis
| Autor: | Eisha A Christian, Mark M. Urata, Thomas Imahiyerobo, J. Gordon McComb, Alexis L. Johns, Pedro A. Sanchez-Lara, Mark D. Krieger |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Birth weight Developmental Disabilities Gestational Age 030230 surgery Bayley Scales of Infant Development Risk Assessment Severity of Illness Index Facial Bones Cohort Studies 03 medical and health sciences Craniosynostoses 0302 clinical medicine Sex Factors Pregnancy Risk Factors Intensive Care Units Neonatal Severity of illness Preoperative Care medicine Humans Monitoring Physiologic Retrospective Studies business.industry Incidence Age Factors Infant Newborn Gestational age Infant Plastic Surgery Procedures medicine.disease Prognosis Gestational diabetes Socioeconomic Factors Premature birth 030220 oncology & carcinogenesis Multivariate Analysis Premature Birth Surgery Female business Cohort study |
| Zdroj: | Plastic and reconstructive surgery. 143(1) |
| ISSN: | 1529-4242 |
| Popis: | Background Some patients with isolated sagittal craniosynostosis have demonstrated mild neurodevelopmental delays. This study examined potential preoperative risk factors for developmental delay. Methods Patients completed preoperative Bayley Scales of Infant and Toddler Development, Third Edition, and medical records were reviewed. Multivariate analyses of covariance and correlations were calculated. Results Participants (n = 77) were predominantly male (77.9 percent) and were aged 2 to 12 months (mean, 5.1 ± 2.3 months). Patients were classified with no delays [n = 63 (82 percent)] or delays [n = 14 (18 percent)] in one or more developmental area(s). There were no group sociodemographic differences. Prenatally, patients with delays versus no delays had lower mean gestational age in weeks (36.9 ± 2.8 weeks versus 39.1 ± 1.7 weeks; p = 0.001) with higher rates of gestational diabetes (36 percent versus 5 percent; p = 0.006) and premature rupture of membranes (14 percent versus 2 percent; p = 0.026). At birth, patients with delays had lower mean birth weight (2982 ± 714 g versus 3374 ± 544 g; p = 0.053), higher rates of respiratory distress (29 percent versus 5 percent; p = 0.005), additional medical diagnoses (57 percent versus 13 percent; p = 0.001), and longer mean neonatal intensive care unit stays (1.4 ± 1.8 weeks versus 0.2 ± 0.9 week; p = 0.002). Variables differing by group had moderate correlations. Conclusions Patients with nonsyndromic sagittal craniosynostosis that had delays in development had lower gestational age and birth weight, with more prenatal and birth complications. These factors can help identify patients who might be at risk for delay and need close monitoring. Clinical question/level of evidence Risk, III. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|