| Popis: |
Lukyanchenko OleksandrI., Mel’nyk OksanaI., GozhenkoOlenaA.,ZukowWalery, Popovych Igor L. Features of the HRV, endocrine and metabolic parameters in persons whose immune status is susceptible or resistant to chronic stress. Journal of Education, Health and Sport. 2020;10(3):177-187. eISSN 2391-8306. DOIhttp://dx.doi.org/10.12775/JEHS.2020.10.03.020 https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2020.10.03.020 https://zenodo.org/record/3753225 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2020; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 05.02.2020. Revised: 15.02.2020. Accepted: 27.03.2020. FEATURES OF THE HRV, ENDOCRINE AND METABOLIC PARAMETERS IN PERSONS WHOSE IMMUNE STATUS IS SUSCEPTIBLE OR RESISTANT TO CHRONIC STRESS OleksandrI. Lukyanchenko1, OksanaI. Mel’nyk2, OlenaA. Gozhenko1, WaleryZukow3, Igor L. Popovych1,4 1Ukrainian Scientific Research Institute of Medicine for Transport, Odesa, Ukrainesofia.lukyanchenko@gmail.com; eago@ukr.net 2Danylo Halyts’kyǐ National Medical University, L’viv,Ukraineomelnyk7@gmail.com 3Nicolaus Copernicus University, Torun, Poland w.zukow@wp.pl 4OO Bohomolets’ Institute of Physiology, Kyїv, Ukrainei.popovych@biph.kiev.ua Abstract Background.In the previous studies, we compared the individuals who were almost identical to the average value of LF/HF ratio and its dispersion, but with opposite deviations from the norm of immunity.Two profiles of EEG have been created that reflect the differences between the two clusters. The first profile contains the parameters that in stress-sensitive individuals are in the zone of narrowed norm, whereas in stress-resistant individuals they are to some degree elevated, or at least exceed those in stress-sensitive individuals. The second profilecontains EEG parameters, each of which in stress-resistant individuals is lower than that of stress-sensitive individuals.The purpose of this study is to clarify the featuresof the HRV, endocrine and metabolic parameters in persons whose immune status is susceptible or resistant to chronic stress.Materials and Methods.The object of observationwere 32men and 8women with chronic pyelonephritis inremission. The criterion for inclusion was the magnitude of the sympathico-vagal balance index LF/HF which exceeded the age norm by 0,5 σ. We determined spectral parameters of HRV, plasma levels of principal adaptation Hormones,plasma and daily urine levels of the Electrolytes and Nitrous metabolites as well as plasma Lipoproteines spectrum. Results. Discriminant analysis revealed that Testosterone is the main factor that conditioning the sensitivity of immune status to sympathotonic shift in autonomic regulation in chronic stress. Sensitizing (immunosuppressive) factors are also Ca/K-ratio of plasma and total Cholesterol, instead LD LP Cholesterol, Creatininuria, P/Ca-ratio of urine, spectral power of VLF band HRV as well as entropy of HRV are desensitizing (immunoprotective) factors. Conclusion. The susceptibility or resistance of the immune status to the stress sympathotonic shift of autonomic regulation is conditioned by the combination of EEG, HRV, endocrine and metabolic parameters. Keywords: Chronic Stress;Immunity;HRV;Hormones;Metabolism. |
