Plexin C1: A novel screening test for lung cancer

Autor:	Duygu Mergan Iliklerden, Buket Mermit Çilingir
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	biology Screening test business.industry Plexin Respiratory System medicine.disease Solunum Sistemi biology.protein Cancer research Medicine Biomarker (medicine) Lung cancer Plexin C1 Biomarker Tumor business Lung cancer
Zdroj:	Volume: 5, Issue: 8 795-798 Journal of Surgery and Medicine
ISSN:	2602-2079
Popis:	Background/Aim: Lung cancer, where early diagnosis is particularly important, is one of the leading causes of death worldwide. Unfortunately, patients with lung cancer present at advanced stages. Biomarkers are needed to detect cancer at an earlier stage. In the present study, we aimed to emphasize that Plexin C1 level can be used in the early diagnosis of patients with lung cancer.Methods: This prospective case-control study included 50 patients with lung cancer who presented between May 2020-September 2020 (25 males and 25 females) in the patient group and 40 healthy individuals (23 males and 17 females) in the control group. All patients with lung cancer underwent routine preoperative tests. Additionally, the preoperative Plexin C1 levels of all patients were measured with the ELISA method and compared between the patient and control groups, and with respect to cancer staging.Results: The median Plexin C1 levels in the patient and control groups were 9.5 ng/mL and 4.0 ng/mL, respectively (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7039b4198e043b82e8261faceb23290 https://dergipark.org.tr/tr/pub/josam/issue/64415/955975 Zobrazit plný text záznamu