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Tissues from 46 white males from the Cincinnati area have been analyzed for lead content. Tissue sections and procedures were standardized and detailed information was obtained in order to account for variables such as age, postmortem changes, type of death and pathological conditions. This report focuses on the lead concentrations found in 29 tissues from each person deceased, including their changes with age, and compares the results with those found in the literature. Although lead concentrations in calcified tissues increased with age, in several tissues the lead concentrations decreased. Some of these decreases were associated with aging and pathological changes. Dense bone lead content increased steadily with age, while spongy bone lead leveled off or decreased in later years. The apparent body burden of lead of this population sample was less than that reported by others. Many of these individuals (70% or more) seemed to be in lead balance with their environment. |
