Involvement of GABAA receptor in modulation of jaw muscle activity evoked by mustard oil application to the rat temporomandibular joint
| Autor: | Brian E. Cairns, James W. Hu, Kenji Seo, Genji Someya |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Male
Microinjections Electromyography Pharmacology Bicuculline Drug Administration Schedule Functional Laterality GABA Antagonists Rats Sprague-Dawley medicine Noxious stimulus Animals Plant Oils Molecular Biology Injections Spinal Plants Medicinal Temporomandibular Joint integumentary system medicine.diagnostic_test Masseter Muscle Plant Extracts GABAA receptor business.industry General Neuroscience Antagonist Receptors GABA-A Rats Temporomandibular joint Electrophysiology medicine.anatomical_structure Anesthesia Masticatory Muscles Reflex Neurology (clinical) business Mustard Plant Developmental Biology medicine.drug |
| Zdroj: | Brain Research. 892:198-202 |
| ISSN: | 0006-8993 |
| DOI: | 10.1016/s0006-8993(00)03283-2 |
| Popis: | The effect of intrathecal administration of the GABAA receptor antagonist bicuculline methylbromide on jaw muscle electromyographic (EMG) activity evoked by mustard oil injection into the rat temporomandibular joint was studied. Bicuculline given prior to mustard oil augmented the EMG activity evoked by mustard oil, and ‘rekindling’ of EMG activity was induced by bicuculline given 30 min after mustard oil. These results suggest that central GABAA receptors modulate reflex responses to noxious craniofacial stimuli. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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