A retrospective study of pituitary-thyroid interaction in patients with first-episode of bipolar disorder type I in Mania State
| Autor: | Fang Wang, Yi Han, Tao Huang, Huaihui Zhang, Yuncheng Zhu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male endocrine system Pituitary gland medicine.medical_specialty China Thyroid Hormones Bipolar Disorder Thyroid Gland Thyrotropin 03 medical and health sciences 0302 clinical medicine Anterior pituitary Pituitary Gland Anterior Internal medicine medicine Humans 030212 general & internal medicine Retrospective Studies First episode Feedback Physiological Triiodothyronine business.industry Thyroid General Medicine Prolactin Mania Thyroxine medicine.anatomical_structure Endocrinology 030220 oncology & carcinogenesis Case-Control Studies Female medicine.symptom business hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Medicine. 100(6) |
| ISSN: | 1536-5964 |
| Popis: | Bipolar disorder (BD)-mania is related to the dysfunction of anterior pituitary gland, but the pituitary-thyroid interaction on the acute stage of BD has been controversial. In order to rule out the effects of drugs, we aimed to determine the upstream interaction of first-episode of BD type I in mania state, and tried to find the relationship between thyroid-stimulating-hormone (TSH) and Prolactin (PRL)This study included 70 real-world patients diagnosed with first-episode BD-mania recuited and 70 healthy controls (HC) matched for age and sex from 2016 to 2017 in the same district of Shanghai. We compared the levels of thyroid hormones and prolactin between the two groups, and linear regression and curve estimation were used for the correlation analysis of TSH and PRLThere were differences in triiodothyronine (TT3), total thyroxin (TT4), and free thyroxine (FT4) concentrations between the groups (P's |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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