Distribution of Chlamydia trachomatis ompA genovars and the new variant of C. trachomatis in the Göteborg area, Sweden
| Autor: | L. Lindholm, Magnus Unemo, P. Tunbäck, Ronza Hadad, Teresa Lagergård, G.-B. Löwhagen |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Microbiology (medical) Serotype Sexually transmitted disease Adolescent Chlamydia trachomatis Biology medicine.disease_cause law.invention Microbiology law Genotype medicine Humans Chlamydiaceae Polymerase chain reaction Sweden Chi-Square Distribution General Medicine Chlamydia Infections Middle Aged New variant biology.organism_classification Virology Infectious Diseases Chlamydiales Mutation Female Bacterial Outer Membrane Proteins |
| Zdroj: | European Journal of Clinical Microbiology & Infectious Diseases. 29:609-611 |
| ISSN: | 1435-4373 0934-9723 |
| DOI: | 10.1007/s10096-010-0887-1 |
| Popis: | The aims of this study were to assess the proportion of the new variant of Chlamydia trachomatis (nvCT) and the distribution of ompA genovars among C. trachomatis-positive patients in the Göteborg area, Sweden. Consecutive urine samples positive for C. trachomatis using BD ProbeTec ET (177 patients, 88 men and 89 women) were collected. An nvCT-specific real-time polymerase chain reaction (PCR) assay was used to investigate the nvCT prevalence. To identify the genovars, a 990-bp ompA DNA segment from 105 specimens was sequenced. Seventeen percent (30/177) of all specimens contained nvCT. Nine different genovars were identified. About 50% were of genovar E, followed by F 16%, G 11%, K 8%, and D 5%, representing about 90% of the specimens in Göteborg. The occurrence of nvCT and the dominance of genovar E in Göteborg is similar to those in other areas of Sweden. To cover about 90% of the C. trachomatis infections in Sweden, the serovars D, E, F, G, and K should be included in future vaccines based on the major outer membrane protein. |
| Databáze: | OpenAIRE |
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