Dispersive micro-solid phase extraction combined with gas chromatography–chemical ionization mass spectrometry for the determination of N-nitrosamines in swimming pool water samples
| Autor: | Yu Chen Wang, Wang Hsien Ding, Ssu Chieh Fu, Shin Hwa Tzing, Hsin Chang Chen |
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| Rok vydání: | 2012 |
| Předmět: |
Chemical ionization
Nitrosamines Chromatography Solid Phase Extraction Extraction (chemistry) Analytical chemistry Water Molecular sieve Biochemistry Gas Chromatography-Mass Spectrometry Dimethylnitrosamine Analytical Chemistry chemistry.chemical_compound Swimming Pools Adsorption chemistry Limit of Detection Solid phase extraction Gas chromatography Gas chromatography–mass spectrometry Water Pollutants Chemical Dichloromethane |
| Zdroj: | Analytical and Bioanalytical Chemistry. 402:2209-2216 |
| ISSN: | 1618-2650 1618-2642 |
| DOI: | 10.1007/s00216-011-5681-0 |
| Popis: | A simple sample pretreatment technique, dispersive micro-solid phase extraction, was applied for the extraction of N-nitrosodimethylamine (NDMA) and other four N-nitrosamines (NAs) from samples of swimming pool water. The parameters affecting the extraction efficiency were systematically investigated. The best extraction conditions involved immersing 75 mg of carbon molecular sieve, Carboxen™ 1003 (as an adsorbent), in a 50-mL water sample (pH 7.0) containing 5% sodium chloride in a sample tube. After 20 min of extraction by vigorous shaking, the adsorbent was collected on a filter and the NAs desorbed by treatment with 150 μL of dichloromethane. A 10-μL aliquot was then directly determined by large-volume injection gas chromatography with chemical ionization mass spectrometry using the selected ion storage mode. The limits of quantitation were |
| Databáze: | OpenAIRE |
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