Practical guidelines on the use of insulin lispro in elderly diabetic patients
| Autor: | Pamela Prescott, Mahmoud M Benbarka, Thomas T. Aoki |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
endocrine system diseases medicine.medical_treatment Diabetes mellitus Internal medicine Insulin Secretion medicine Insulin lispro Humans Hypoglycemic Agents Insulin Pharmacology (medical) Pancreatic hormone Aged Glucose tolerance test Type 1 diabetes Insulin Lispro medicine.diagnostic_test business.industry nutritional and metabolic diseases Type 2 Diabetes Mellitus Glucose Tolerance Test medicine.disease Combined Modality Therapy Endocrinology Postprandial Diabetes Mellitus Type 1 Diabetes Mellitus Type 2 Practice Guidelines as Topic Geriatrics and Gerontology business medicine.drug |
| Zdroj: | Drugsaging. 12(2) |
| ISSN: | 1170-229X |
| Popis: | Glucose tolerance deteriorates, and the prevalence of diabetes mellitus increases, with advancing age. Most elderly diabetic patients have type 2 (non—insulin-dependent) diabetes mellitus, but the prolonged survival of young people with type 1 (insulin-dependent) diabetes mellitus increases the prevalence of type 1 diabetes among the elderly. Approximately 25 to 29% of patients with type 2 diabetes mellitus are treated with insulin. Conventional therapy with regular and intermediate-acting insulin preparations does not mimic physiological insulin secretion. Subcutaneous administration of insulin lispro, a recently introduced insulin analogue, more closely mimics the time-action curve of endogenous insulin that is produced in response to meals. Its rapid onset and short duration of action allow for adequate control of postprandial glucose levels while reducing the risk of late postprandial hypoglycaemia. Insulin lispro offers improved glycaemic control, convenience and increased flexibility in insulin-treated patients with diabetes. |
| Databáze: | OpenAIRE |
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