Administration of Ondansetron Is Associated With Lethal Outcome

Autor:	Jarrett M Burns, Blanca Gener, Edward W. Boyer, Susanne Griffin
Rok vydání:	2010
Předmět:	Male Oncology medicine.medical_specialty Fatal outcome Vomiting Ondansetron Fatal Outcome Text mining Therapeutic index Internal medicine Diseases in Twins medicine Humans Genetic Predisposition to Disease Muscular abnormality Triplets business.industry Malignant hyperthermia Ryanodine Receptor Calcium Release Channel Twins Monozygotic medicine.disease Child Preschool Pharmacodynamics Pediatrics Perinatology and Child Health Antiemetics Malignant Hyperthermia business Myopathies Structural Congenital medicine.drug
Zdroj:	Pediatrics. 125:e1514-e1517
ISSN:	1098-4275 0031-4005
DOI:	10.1542/peds.2009-2795
Popis:	We report here the case of a child with a known muscular abnormality and susceptibility to malignant hyperthermia who abruptly died after receiving a therapeutic dose of ondansetron. Also, we discuss the pharmacodynamic relationship of ondansetron to malignant hyperthermia in a susceptible host.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6da27a0445e26e46f7d2c30bd653799 https://doi.org/10.1542/peds.2009-2795 Zobrazit plný text záznamu