Laminin and type III procollagen peptide in human preovulatory follicular fluid

Autor: Rene Lambotte, Demoulin A, Jean-Michael Foidart, Fernand Leroy, Daniel Gillain, Charles Maurice Lapiere, Betty V. Nusgens, Y. Christiane
Rok vydání: 1988
Předmět:
Zdroj: Fertility and sterility. 50(1)
ISSN: 0015-0282
Popis: The levels of laminin PI fragment, a marker of basement membrane, and of the aminoterminal sequence of type III procollagen, a marker of interstitial connective tissue, were measured in human preovulatory follicular fluids. The concentrations of these peptides correlated with progesterone levels but not with those of estradiol or testosterone. Immunocytochemical studies confirmed the remodeling of the perifollicular basement membrane and interstitial matrix during oocyte maturation. The studies suggest that monitoring of the ovarian connective tissue macromolecules could be useful for estimating follicular maturation.
Databáze: OpenAIRE