Upgrade rate of intraductal papilloma without atypia on breast core needle biopsy: A clinical, radiological and pathological correlation study
| Autor: | Sabina Hajiyeva, Panagiotis A. Manolas, Bugra Tugertimur, Adnan Hasanovic, Iskender Sinan Genco |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Breast Neoplasms Papilloma Intraductal 03 medical and health sciences 0302 clinical medicine Intraductal papilloma medicine Atypia Humans Correlation of Data skin and connective tissue diseases Pathological correlation Aged Aged 80 and over Invasive carcinoma business.industry Cancer General Medicine Middle Aged Ductal carcinoma medicine.disease 030220 oncology & carcinogenesis Radiological weapon Breast core needle biopsy Female 030211 gastroenterology & hepatology Surgery Biopsy Large-Core Needle Radiology Neoplasm Grading business |
| Zdroj: | The American Journal of Surgery. 220:677-681 |
| ISSN: | 0002-9610 |
| Popis: | Background The aim of the study was to determine the upgrade rate on excision of intraductal papilloma (IDP) without atypia diagnosed on breast core needle biopsy (CNB). Methods We searched our pathology department database for breast CNB with a diagnosis of IDP from 2013 to 2018. The exclusion criteria included radiologic-pathologic discordance, atypia on the same CNB, absence of histologic slides to review or absence of excision information. Upgrade was defined as ductal carcinoma in situ (DCIS) or invasive cancer identified on excision. Results 126 IDP without atypia cases from 94 patients were identified. The upgrade rate was 1.58% (2/126). Both upgrade cases showed DCIS with low and intermediate nuclear grade. Histologic size of IDP ≥1 cm was the only statistically significant predictor factor for an upgrade on excision. Conclusion The results suggest that non-surgical management of patients with radiologic-pathologic concordant IDP without atypia diagnosed on CNB may be appropriate in routine practice. |
| Databáze: | OpenAIRE |
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