Current status of rotavirus vaccines
Autor: | Kow-Tong Chen, Shou-Chien Chen, Ching-Min Wang |
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Rok vydání: | 2014 |
Předmět: |
Rotavirus
Pediatrics medicine.medical_specialty Cost effectiveness viruses Cost-Benefit Analysis MEDLINE Developing country English language medicine.disease_cause Vaccines Attenuated Rotavirus Infections fluids and secretions Environmental health medicine Humans Child Developing Countries business.industry Infant Newborn Rotavirus Vaccines virus diseases Infant Rotavirus vaccine Gastroenteritis Vaccination Diarrhea Child Preschool Pediatrics Perinatology and Child Health medicine.symptom business |
Zdroj: | World journal of pediatrics : WJP. 11(4) |
ISSN: | 1867-0687 |
Popis: | Rotaviruses remain the major cause of childhood diarrheal disease worldwide and of diarrheal deaths of infants and children in developing countries. The huge burden of childhood rotavirus-related diarrhea in the world continues to drive the remarkable pace of vaccine development. Research articles were searched using terms "rotavirus" and "rotavirus vaccine" in MEDLINE and PubMed. Articles not published in the English language, articles without abstracts, and opinion articles were excluded from the review. After preliminary screening, all articles were reviewed and synthesized to provide an overview of current vaccines and vaccination programs. In this review of the global rotavirus vaccines and vaccination programs, the principles of rotavirus vaccine development and the efficacy of the currently licensed vaccines from both developed and developing countries were summarized. Rotavirus is a common cause of diarrhea in children in both developed and developing countries. Rotavirus vaccination is a cost-effective measure to prevent rotavirus diarrhea. |
Databáze: | OpenAIRE |
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