Bilateral Anterior Capsulotomy for Refractory Obsessive-Compulsive Disorders

Autor: Rodrigo Rodriguez, Josep Gascón, Alberto Aparicio, Bartolome Oliver, Pere Anton Soler, Emilio Ayats, Marcel García-Bach, Juan Luis Maestro de León
Rok vydání: 2003
Předmět:
Zdroj: Stereotactic and Functional Neurosurgery. 81:90-95
ISSN: 1423-0372
1011-6125
DOI: 10.1159/000075110
Popis: A prospective study on the effects of bilateral anterior capsulotomy in patients with refractory obsessive-compulsive disorder (OCD) is presented. A total of 18 procedures were performed in 15 patients. The mean duration of the OCDs was 18.1 ± 5.6 years (range 11–26 years). The mean total Yale-Brown Scale (Y-BOCS) score was 29.67 and mean Global Assessment of Functioning was 43.61. The results throughout the follow-up period remained the same as at 1 month postoperatively. The observed mean recovery on the Y-BOCS was 33.2% (p = 0.017). 52.9% of the patients showed a 33% recovery, 29.4% of the cases showed a 50% recovery and 17% showed a 66% recovery. Global Assessment of Functioning recovered by 19% (p = 0.111). No cognitive deficit was disclosed by neuropsychological screening tests. Complications were observed in 3 cases, 1 with transitory hallucinations, 1 with a single epileptic seizure and 1 case who developed a progressive behavior disorder that became permanent. We conclude that bilateral anterior capsulotomy is a safe and effective procedure.
Databáze: OpenAIRE