| Autor: |
Diana Kut, Mykola Kut, Oleg Svalyavin, Mikhajlo Onysko, Vasil Lendel |
| Rok vydání: |
2022 |
| Předmět: |
|
| DOI: |
10.6084/m9.figshare.20038292.v1 |
| Popis: |
The regioselectivity of halogenation of terminal and internal thioethers of 7-(trifluoromethyl)quinazolin-4(3H)-ones was investigated. It is proven that the direction of halocyclization of allyl thioethers depends on the presence of a substituent at the terminal carbon atom of the allyl moiety. The cyclization of allyl, methallyl and prenyl thioethers leads to the annulation of thiazole cycle with the formation of thiazolo[3,2-a]quinazolinium trihalides while cyclization of cinnamyl thioether forms thiazino[3,2-a]quinazolinium trihalides with the additional thiazine cycle. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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