Gestational and Postpartum Weight Trajectories Among Women With and Without Asthma
Autor: | Zhen Chen, Stefanie N. Hinkle, Rajesh Kumar, Leah M. Lipsky, Andrew D. Williams, Jenna Kanner, Danielle R. Stevens, Seth Sherman, Pauline Mendola, William A. Grobman, Matthew C.H. Rohn |
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Rok vydání: | 2020 |
Předmět: |
Adult
medicine.medical_specialty Epidemiology Context (language use) Body Mass Index 03 medical and health sciences 0302 clinical medicine Pregnancy immune system diseases medicine Humans Prospective Studies 030212 general & internal medicine Asthma Exercise-induced asthma Models Statistical business.industry Obstetrics Postpartum Period Original Contribution medicine.disease Obesity Gestational Weight Gain United States respiratory tract diseases 030228 respiratory system Body-Weight Trajectory Female medicine.symptom business Body mass index Weight gain Postpartum period |
Zdroj: | Am J Epidemiol |
ISSN: | 1476-6256 0002-9262 |
Popis: | Asthma leads to increased weight gain in nonpregnant populations, but studies have not examined this association within the context of pregnancy. The association between asthma and perinatal weight trajectories was examined in the Breathe—Wellbeing, Environment, Lifestyle, and Lung Function Study (2015–2019). Multilevel linear spline models were adjusted for age, race/ethnicity, income, marital status, education, cigarette smoking, parity, study site, and prepregnancy body mass index were used to examine differences in perinatal weight trajectories between women with (n = 299) and without (n = 101) asthma. Secondary analyses were conducted to assess whether associations differed by asthma phenotypes. At 40 weeks’ gestation, women with asthma gained 16.2 kg (95% confidence interval (CI): 14.6, 17.7) and women without asthma gained 13.1 kg (95% CI: 10.9, 15.4). At 3 months postpartum, women with asthma retained 10.4 kg (95% CI: 8.9, 11.9) and women without asthma retained 8.0 kg (95% CI: 5.9, 10.2). Among women with asthma, exercise-induced asthma and step 3 asthma medications were associated with excess gestational weight gain. These study findings suggest women with asthma gain and retain more weight during pregnancy and postpartum than do women without asthma. |
Databáze: | OpenAIRE |
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