Conformational Studies of Oxytocin and Lysine Vasopressin in Aqueous Solution using High Resolution NMR Spectroscopy
| Autor: | James Feeney, J. H. Rockey, Arnold S. V. Burgen, Gordon C. K. Roberts |
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| Rok vydání: | 1971 |
| Předmět: |
Vasopressin
Magnetic Resonance Spectroscopy Aqueous solution Vasopressins Hydrogen bond Chemistry Stereochemistry Lysine Inorganic chemistry General Medicine Oxytocin Ring (chemistry) General Biochemistry Genetics and Molecular Biology Intramolecular force Proton NMR medicine Amino Acid Sequence Protons Peptides Spectroscopy hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Nature New Biology. 232:108-110 |
| ISSN: | 2058-1092 0090-0028 |
| Popis: | 1H NMR measurements of oxytocin and lysine vasopressin in H20 solution indicate that they have similar conformations. There is no evidence for intramolecular hydrogen bonding, nor for the Pro-Leu(Lys)-GlyNH2 fragment being folded over the ring. Some details of the conformation of oxytocin, vasopressin and their reduced forms are discussed in this article. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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