Prevention of venous thromboembolism with low doses of heparin in urologic patients

Autor: Marijan Radej, Damir Grgičević, Marijan Pistotnik, Marijan Kovačić
Rok vydání: 1977
Předmět:
Zdroj: Urology. 9(3)
ISSN: 0090-4295
Popis: The effectiveness of low doses of heparin was investigated for the prevention of clinically manifested thromboembolic disease. In the group of 125 patients, who received 5,000 units of subcutaneous heparin two hours before the operation, and postoperatively 15,000 units per day for seven to ten days, deep vein thrombosis was not observed, and in only 1 patient (0.8 per cent) pulmonary embolism was suspected. Of 216 patients from the control group, pulmonary embolism was clinically diagnosed in 4 (1.9 per cent), deep vein thrombosis in 7 (3.4 per cent), and in 2 patients (0.9 per cent) fatal pulmonary embolism was found at autopsy. The difference between total thromboembolic disease of the control group (6.2 per cent) and heparinized group was highly significant (p < 0.02). Postoperative bleeding was seen two times more often in the heparin group, but bleeding was not severe and was easily controlled.
Databáze: OpenAIRE