Venomous auger snailHastula (Impages)hectica (Linnaeus, 1758): molecular phylogeny, foregut anatomy and comparative toxinology
| Autor: | Bradford J. Stevenson, Karin M Hansson, Francisco M. Heralde, Johan Stenflo, Julita S. Imperial, Yuri I. Kantor, Ping Chen, John-Paul Ownby, Baldomero M. Olivera, Maren Watkins, Philippe Bouchet |
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| Rok vydání: | 2007 |
| Předmět: |
DNA
Complementary Toxinology Molecular Sequence Data Snails Mollusk Venoms Venom Snail complex mixtures Monophyly biology.animal Conus Genetics Animals Conoidea Amino Acid Sequence Phylogeny Ecology Evolution Behavior and Systematics Terebridae Hastula biology Anatomy biology.organism_classification Gastrointestinal Tract Molecular Medicine Animal Science and Zoology Developmental Biology |
| Zdroj: | Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. :744-756 |
| ISSN: | 1552-5015 1552-5007 |
| DOI: | 10.1002/jez.b.21195 |
| Popis: | The > 10,000 living venomous marine snail species [superfamily Conoidea Fleming, 1822] include cone snails (Conus), the overwhelming focus of research. Hastula hectica (Linnaeus, 1758), a venomous snail in the family Terebridae Morch, 1852 was comprehensively investigated. The Terebridae comprise a major monophyletic group within Conoidea. H. hectica has a striking radular tooth to inject venom that looks like a perforated spear; in Conus, the tooth looks like a hypodermic needle. H. hectica venom contains a large complement of small disulfide-rich peptides, but with no apparent overlap with Conus in gene superfamilies expressed. Although Conus peptide toxins are densely post-translationally modified, no post-translationally modified amino acids were found in any Hastula venom peptide. The results suggest that different major lineages of venomous molluscs have strikingly divergent toxinological and venom-delivery strategies. J. Exp. Zool. (Mol. Deu. Euol.) 308B: 744- 756, 2007. (c) 2007 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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