The national burden of influenza-associated severe acute respiratory illness hospitalization in Zambia, 2011-2014
| Autor: | Andros Theo, Stefano Tempia, Adam L Cohen, Paul Simusika, Edward Chentulo, Chikama Mukwangole Chikamukwa, Mwaka Monze |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Pulmonary and Respiratory Medicine Adult Adolescent Epidemiology 030106 microbiology Zambia burden 03 medical and health sciences Young Adult 0302 clinical medicine Risk Factors Influenza Human Humans 030212 general & internal medicine Child Pandemics Aged Retrospective Studies Public Health Environmental and Occupational Health Infant Original Articles Middle Aged severe acute respiratory illness Hospitalization Infectious Diseases Influenza Vaccines Child Preschool Original Article influenza Sentinel Surveillance |
| Zdroj: | Influenza and Other Respiratory Viruses |
| ISSN: | 1750-2659 |
| Popis: | Background Estimates of influenza‐associated hospitalization are limited in low‐ and middle‐income countries, especially in Africa. Objective To estimate the national number of influenza‐associated severe acute respiratory illness (SARI) hospitalization in Zambia. Methods We conducted active prospective hospital‐based surveillance for SARI at the University Teaching Hospital (UTH) situated in Lusaka Province during 2011‐2014. Upper respiratory tract samples were tested for influenza virus using a reverse transcriptase polymerase chain reaction assay. We estimated age‐specific rates of influenza‐associated SARI hospitalizations for the UTH using census and secondary data on respiratory hospitalizations following estimation approaches recommended by the World Health Organization. We used the UTH hospitalization rates as a proxy for Lusaka Province. These rates were adjusted for each of the remaining 9 provinces based on their prevalence of risk factors for pneumonia and healthcare‐seeking behavior. Rates were expressed per 100,000 population. Results SARI cases accounted for 77.1% (13 389/17 354) of respiratory admissions at the UTH; 82.7% (11 859/14 344) and 50.8% (1530/3010) among individuals aged |
| Databáze: | OpenAIRE |
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