Prevalence of hepatitis C virus genotypes in Italy
| Autor: | Pistello, M., Maggi, F., Vatteroni, L., Cecconi, N., Panicucci, F., Bresci, G. P., Gambardella, L., Taddei, Maurizio, Bionda, A., Tuoni, M., Bendinelli, M. |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Microbiology (medical) Hepatitis C Virus Adolescent Genotype Biopsy Hepatitis C virus Molecular Sequence Data Biology Hemophilia A medicine.disease_cause Polymerase Chain Reaction Virus Flaviviridae Prevalence medicine Humans Aged Aged 80 and over Hepatitis Phylogenetic analysis Base Sequence medicine.diagnostic_test HCV Hepatitis C Middle Aged medicine.disease biology.organism_classification Virology Italy Liver Liver biopsy Viral disease Research Article |
| Zdroj: | Journal of Clinical Microbiology. 32:232-234 |
| ISSN: | 1098-660X 0095-1137 |
| DOI: | 10.1128/jcm.32.1.232-234.1994 |
| Popis: | Hepatitis C viruses (HCV) present in 110 Italian patients were characterized by genotype-specific PCRs. Among the 65 cases of community-acquired hepatitis, HCV genotype II was dominant (60%), followed by genotypes IV (15%), III (11%), and I (3%). Among the 45 hemophilia-associated cases, the distribution of the four HCV genotypes was markedly different: genotype I was the most prevalent (61%), followed by genotypes II (25%), III (4%), and IV (2%). Double infections were observed in eight patients. Two HCV remained unclassified. For the 45 community-acquired cases from which a liver biopsy was available, genotype II was associated with more severe liver damage than the other types. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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