Subtle cognitive deficits after cerebellar infarcts
| Autor: | Oili Salonen, Mervi Kotila, R. O. Roine, V. Kauranen, Laura Hokkanen |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Brain Infarction Male Cerebellum medicine.medical_specialty Time Factors Neuropsychological Tests Audiology Functional Laterality 050105 experimental psychology 03 medical and health sciences 0302 clinical medicine Outcome Assessment Health Care Humans Medicine 0501 psychology and cognitive sciences Neuropsychological assessment Radionuclide Imaging Episodic memory Retrospective Studies Analysis of Variance medicine.diagnostic_test business.industry Working memory 05 social sciences Neuropsychology Cognition Middle Aged Verbal Learning medicine.anatomical_structure Neurology Case-Control Studies Laterality Female Neurology (clinical) Verbal memory Cognition Disorders business Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | European Journal of Neurology. 13:161-170 |
| ISSN: | 1468-1331 1351-5101 |
| DOI: | 10.1111/j.1468-1331.2006.01157.x |
| Popis: | The role of the cerebellum in cognitive functions has been under debate. We investigated the neuropsychological functioning of patients with cerebellar lesions (infarcts) and evaluated the significance of laterality in cognitive symptoms. Twenty-six patients with exclusive cerebellar lesions as verified by clinical and neuroradiological findings underwent a neuropsychological assessment at the acute stage and at 3 months. Their performance was compared with 14 controls, also assessed twice. The focus was on four domains: visuospatial/motor functions, episodic memory, working memory and attentional shifting/execution. Both groups improved over time. Statistical differences emerged in tests in the visuomotor domain as well as in the episodic and working memory domains. Patients with left cerebellar lesion were slow in a visuospatial task, whereas those with right cerebellar lesions had verbal memory difficulty compared with controls. By 3 months, 77% of the patients had returned to work, and only one had cognitive impairment and did not return to work. Our results indicate that cerebellar infarcts may result in subtle cognitive changes perhaps primarily related to working memory deficit. The symptoms may be mediated by the contralateral cortical hemisphere, left cerebellar infarcts producing mild right hemispheral dysfunction and right cerebellar infarct producing mild left hemispheral dysfunction. |
| Databáze: | OpenAIRE |
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