The genes coding for the muscle contractile proteins, myosin heavy chain, myosin light chain 2, and skeletal muscle actin are located on three different mouse chromosomes
Autor: | D D Pravtcheva, Moshe Shani, Frank H. Ruddle, David Yaffe, Henryk Czosnek, Uri Nudel, P. E. Barker |
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Rok vydání: | 1982 |
Předmět: |
Myosin light-chain kinase
Macromolecular Substances macromolecular substances Hybrid Cells Myosins Biology Chromosomes General Biochemistry Genetics and Molecular Biology Mice Cricetulus Fetus Cricetinae Myosin medicine Animals Molecular Biology Gene Actin Chromosome 7 (human) Mice Inbred BALB C General Immunology and Microbiology Muscles General Neuroscience Chromosome Mapping Nucleic Acid Hybridization Skeletal muscle DNA Molecular biology Actins Molecular Weight medicine.anatomical_structure Genes Chromosome 3 MYH7 Plasmids Research Article |
Zdroj: | The EMBO Journal. 1:1299-1305 |
ISSN: | 0261-4189 |
DOI: | 10.1002/j.1460-2075.1982.tb01314.x |
Popis: | The chromosomal distribution of murine genes expressed during differentiation of skeletal muscle cells was determined by Southern blot analysis of DNA from mouse-Chinese hamster hybrid cell lines containing incomplete subsets of mouse chromosomes. All detectable myosin heavy chain genes are located on chromosome 11. The gene for the myosin light chain 2 is located on chromosome 7. The skeletal muscle alpha-actin gene and several other actin genes, or pseudogenes, are located on chromosome 3. Additional actin DNA sequences are distributed on other mouse chromosomes. |
Databáze: | OpenAIRE |
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