Effect of Royal Jelly on Bisphenol A-Induced Proliferation of Human Breast Cancer Cells

Autor: Kyoko Sasaki, Hirofumi Tachibana, Koji Yamada, Hiroyuki Onda, Akiko Yukiyoshi, Mako Nakaya
Rok vydání: 2007
Předmět:
Zdroj: Bioscience, Biotechnology, and Biochemistry. 71:253-255
ISSN: 1347-6947
0916-8451
Popis: Royal jelly is known as a functional food containing many useful minerals. In this study, we found an anti-environmental estrogen activity of royal jelly. Bisphenol A (BPA) is an environmental estrogen that stimulates proliferation of human breast cancer MCF-7 cells. Royal jelly inhibited the growth-promoting effect of BPA on MCF-7 cells, even though it did not affect the proliferation of cells in the absence of BPA. In addition, this inhibiting effect of royal jelly was heat-stable.
Databáze: OpenAIRE