Development of resistance to quinolones in five patients with campylobacteriosis treated with norfloxacin or ciprofloxacin
| Autor: | Martin Altwegg, H. Adler-Mosca, A. Burnens, G. Martinetti Lucchini, J. Lüthy-Hottenstein |
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| Rok vydání: | 1991 |
| Předmět: |
Adult
DNA Bacterial Male Microbiology (medical) medicine.medical_specialty Nalidixic acid medicine.drug_class Restriction Mapping Antibiotics Campylobacteriosis Campylobacter coli Biology DNA Ribosomal Microbiology Campylobacter jejuni Nalidixic Acid Medical microbiology Ciprofloxacin Campylobacter Infections medicine Humans Norfloxacin Strain (chemistry) Drug Resistance Microbial General Medicine Ribosomal RNA bacterial infections and mycoses medicine.disease Virology Infectious Diseases Female medicine.drug |
| Zdroj: | European Journal of Clinical Microbiology & Infectious Diseases. 10:953-957 |
| ISSN: | 1435-4373 0934-9723 |
| Popis: | Development of resistance to nalidixic acid, norfloxacin and ciprofloxacin was observed in five patients with Campylobacter jejuni or Campylobacter coli infection. From all these patients nalidixic acid- and quinolone-susceptible strains were isolated initially, whereas after therapy with norfloxacin or ciprofloxacin strains resistant to these antibiotics were found. Campylobacter strains from the same patient always belonged to the same species and, with the exception of one case, showed identical rRNA gene restriction (rDNA) patterns. This indicates that double-infection with a susceptible and a resistant strain was not responsible for the phenomenon but rather that the infecting strain rapidly developed resistance following treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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