The role of substance use and adult sexual assault severity in the course of schizophrenia: An epidemiological catchment study of sexual assault victims
| Autor: | Sharon Rabinovitz, Julia Barda, Paula Rosca, Stephen Z. Levine, Keren Goldman |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Substance-Related Disorders Poison control Suicide prevention Occupational safety and health 03 medical and health sciences 0302 clinical medicine Catchment Area Health Risk Factors Epidemiology Injury prevention medicine Humans Longitudinal Studies Risk factor Israel Psychiatry Biological Psychiatry business.industry Sex Offenses Human factors and ergonomics social sciences medicine.disease 030227 psychiatry Psychiatry and Mental health Schizophrenia Female Schizophrenic Psychology business 030217 neurology & neurosurgery |
| Zdroj: | Schizophrenia research. 208 |
| ISSN: | 1573-2509 |
| Popis: | Background Childhood trauma increases the risk of schizophrenia, yet the role of adult sexual assault in the course of schizophrenia is unknown. This study aims to examine the associations between substance use and sexual assault severity characteristics with the course of schizophrenia among adult sexual assault victims using an epidemiologic study design. Methods Sexual assault data on all individuals received from 2000 to 2010 (N = 2147) at the Center for Care of Sexual Assault Victims at Wolfson Medical Center, the largest medical center for sexual assault victims in the country, were merged with the Israel National Psychiatric Case Registry, that consisted of lifetime psychiatric hospitalizations of schizophrenia (birth to 6 years post-assault). The associations between substance use and adult sexual assault severity characteristics with hospitalizations were quantified using recurrent events Cox modeling. Results Schizophrenia with sexual assault survivors occurred in 117 persons. Cox modeling showed that recurrent psychiatric hospitalizations were associated with younger age, sexual assault at older age, previous diagnosis of psychosis, and drug use shortly before or during the assault. Other assault characteristics (number of assailants, means of subdual, penetration type, perpetrator violence, physical injury of the victim) and immediacy of seeking help had a null association with the course of psychiatric hospitalization. These results replicated in two sensitivity analyses. Conclusions Substance use among victims of sexual assault was associated with an exacerbated course of schizophrenia, pointing to a possibly modifiable risk factor that should be targeted in prevention, assessment, treatment formulation and implementation. |
| Databáze: | OpenAIRE |
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